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Extra resources for Active Transport through Animal Cell Membranes

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But this probably is by way of a mucus gland secretion. JORGENSEN, LEVI, and USSING (1947) examined the action of neurohypophyseal principles (from the ox) on intact axolotls in a circulating system of very dilute, labelled NaCl. Injection of the pressor principle induced a rather protracted net uptake of salt while the oxytocic principle caused a rapid and prolonged loss. KOEFoED- JOHNSEN and USSING (1949) found in the same preparation a large progressive uptake of CI- following injection of a corticotropin preparation from the beef pituitary; the Na 24 influx was doubled or tripled for several days by this treatment.

The Na+ efflux concurrently determined with Na 22 just about accounted for the difference between the two figures, so that the entire short-circuit current was attributable to active Na+ transport. This experimental system further permitted the calculation of the electromotive force and internal resistance of the "sodium battery," LINDERHOLM (1952), using similar methods in TeoreH's laboratory, showed that the combined conductances for Na+ and CI- account for the electrically estimated total conductance for the frog skin.

With this agent, the short-circuited skin current may nearly double and this increment appears to be essentially an outward CI- transport, as KOEFOEDJOHNSEN, USSING, and ZERAHN (1952) showed with simultaneous determinations of influx and outflux with Cl36 and CP3. But this probably is by way of a mucus gland secretion. JORGENSEN, LEVI, and USSING (1947) examined the action of neurohypophyseal principles (from the ox) on intact axolotls in a circulating system of very dilute, labelled NaCl. Injection of the pressor principle induced a rather protracted net uptake of salt while the oxytocic principle caused a rapid and prolonged loss.

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