Download Advances in Genetics, Vol. 19 by E.W. Caspari (Ed.) PDF

By E.W. Caspari (Ed.)

This quantity in a chain on genetics, emphasizes the variety of genetic experiences. Articles disguise the filamentous fungus neurospora, biogenesis of yeast ribosomes, evolutionary genetics of fish, drosophila transposable components and the dropophila gene zeste.

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ZuA + + adG + + + + proA2 + + - 1 - pro-94 proA2 + pro-94 proA2 + pro-94 - + + YA + + + + adE yA adE YA adE + + yA adE yA adE + + + + + yA adE yA adE + + + adE + yA adE + + + + + + + + + + + + + + + + + + + + biA + + biA + AcrA wA + + Acra wA AcrA wA + + AcrA wA AcrA wA + + AcrA wA AcrA wA + + AcrA wA - A 70 ETTA KAFER coincidence of crossing-over and nondisjunction. , the close markers EysF in I R and luA in I L) in no case was there evidence for any type of segregation in these yellow or suppressed pro-types other than “single crossing-over” on either side of proA (the genotypes of all, or a t least ten, pro segregants from both selections from every test diploid were analyzed by haploidization) .

9 ) . Segregants of this type have been analyzed in large numbers from diploids heterozygous for various markers and for T1 (1;T711)in coupling with the selective marker suAadE [a recessive suppressor used for selection from diploids homozygous for adE, on media lacking adenine; details are shown in Kafer (1976) 1. Recently, diploids with suAadE in repulsion, but fpaA in coupling to T1 ( I ; V I I ) , have also been successfully used to obtain unbalanced fpaA/fpaA crossovers. Such a diploid (as shown in Fig.

2. Nondisjunction Haploid and diploid segregants resulting from misdistribution of whole chromosomes may arise from several processes, especially when inducing agents are used (see below). I n Aspergillus, spontaneous nondisjunction usually involves missegregation of single or few chromosomes, producing trisomics as primary products (see Fig. 5 ) . , compared to diploid crossovers) may differ under different conditions. Haploid segregants are likely to be the result of several steps of chromosomal loss, presumably starting with the 2 n - 1 products which only survive in heterokaryotic condition (Kafer, 1961) (for viability and phenotypes of aneuploids see above, “meiotic” aneuploids) .

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