Download Andrology: Male Reproductive Health and Dysfunction by Eberhard Nieschlag (auth.), Eberhard Nieschlag, Hermann M. PDF

By Eberhard Nieschlag (auth.), Eberhard Nieschlag, Hermann M. Behre, Susan Nieschlag (eds.)

This is the 3rd, absolutely revised version of a widely known textbook that maintains to symbolize the top-rated within the literature on scientific andrology. It examines extensive all elements of male reproductive future health, encompassing the elemental body structure of male reproductive functionality and quite a lot of issues. all the chapters is written via remarkable specialists within the box. one of the subject matters lined are:

  • Testicular function
  • Sperm maturation and fertilization
  • Diagnostic tactics
  • Infertility
  • Primary and secondary hypogonadism
  • Late-onset hypogonadism
  • Erectile dysfunction
  • Genetic disorders
  • Environmental influences
  • Psychology and sexual medicine
  • Testosterone therapy
  • Assisted copy: TESE and ICSI
  • Cryopreservation
  • Male contraception
  • Ethics in andrology

This quantity will function a textbook for the newcomer to andrology, whereas offering the skilled health care professional with a beneficial reference paintings. it's going to entice all who're excited about male reproductive health and wellbeing:

  • Andrologists
  • Urologists
  • Endocrinologists
  • Gynecologists
  • Internists
  • Pediatricians
  • Basic scientists

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Extra resources for Andrology: Male Reproductive Health and Dysfunction

Example text

10 Importance of the pulsatile pattern of GnRH secretion for gonadotropin secretion and testicular function. Unphysiologically high GnRH pulse frequencies or continuous administration of GnRH inhibit gonadotropin secretion and testicular function (red). Similarly, blockade of GnRH receptors by means of GnRH analogs results in suppression of testicular function Pulsatile GnRH GnRH GnRH Pulsatile 2 Physiology of Testicular Function Among the neurotransmitters and neuromodulators that might influence GnRH secretion, the noradrenergic system and NPY show stimulatory activity, whereas interleukin-1, dopaminergic, serotoninergic and GABAergic systems are inhibitory.

The hypothalamus is the rostral extension of the brain stem reticular formation. It contains, among others, the cellular bodies of neurons that project their axon terminals toward the median eminence (ME), a specialized region of the floor of the third ventricle from which the pituitary stalk originates. The hypothalamus is classically subdivided into three longitudinal zones, periventricular, medial and lateral, the latter functioning as the connecting area between limbic and brain stem regions, whereas the former two contain most of the nuclei controlling neuroendocrine and visceral functions.

2003). The succession of all stages along time is called the spermatogenic cycle. The duration of the spermatogenic cycle depends on the animal species and lasts between 8–17 days in mammals. One human spermatogenic cycle requires 16 days. For the development and differentiaton of an Ap spermatogonium into a mature sperm at least four spermatogenic cycles are necessary. It can be deduced that the overall duration of spermatogenesis is calculated as around 50 days in the rat, 37–43 days in different monkey species and at least 64 days in man.

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