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By Satinder Ahuja (Eds.)

content material: Chiral separations : an summary / Satinder Ahuja --
Analytical standards for chiral high-pressure liquid chromatography / Thomas D. Doyle --
Commercially on hand brush-type chiral selectors for the direct solution of enantiomers / S.R. Perrin and W.H. Pirkle --
Chiral separations utilizing local and functionalized cyclodextrin-bonded desk bound levels in high-pressure liquid chromatography / Randy A. Menges and Daniel W. Armstrong --
Chromatographic optical answer on polysaccharide carbamate levels / Yoshio Okamoto, Yuriko Kaida, Ryo Aburatani, and Koichi Hatada --
Protein column-based chiral reversed-phase liquid chromatography / S.G. Allenmark --
Optimization of chiral separations on silica-bonded [alpha]1-acid glycoprotein through cellular section ingredients / E. Arvidsson, S.O. Jansson, and G. Schill --
Chiral reputation on biopolymer-based high-pressure liquid chromatographic chiral desk bound levels : a case for a number of interplay websites / Irving W. Wainer, Terence A.G. Noctor, Enrico Domenici, and Philippe Jadaud --
Chiral separations and modes of organization of hydrogen-bonding molecules / E. Gil-Av --
Liquid chromatographic separation of enantiomers through hydrogen-bond organization / Akira Dobashi, Yasuo Dobashi, and Shoji Hara --
High-pressure liquid chromatographic solution of optical isomers / effect of cellular and [pi]-donor chiral desk bound stages / Subhash C. Dhanesar --
Direct stereochemical high-pressure liquid chromatographic separation of aminoglutethimide and its significant metabolite : its purposes to organic fluids / Hassan Y. Aboul-Enein and M. Rafiqul Islam --
Amino acid racemization : a device for relationship? / Veronika R. Meyer.

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Albumin-silica columns were scaled up to study albumin usefulness f o r preparative purposes. 1 g albumin per g s i l i c a were e a s i l y made. Because of the high molecular weight of the c h i r a l component and the l i m i t e d number of binding s i t e s of each molecule, the capacity of the column, an important f a c t o r , was investigated. Leaching of albumin from the column l i m i t s the use f o r preparative separations, and the contaminat i o n of albumin i n compounds i s o l a t e d from c o l l e c t e d fractions was studied as a function of amount of organic modifier i n the mobile phase.

Vol. 9 (2 & 3), 1986. G. P. Kraft, K. Fickentscher, and F. -Forsch. 29, 1640 (1979). "Top 200 Drugs i n 1982", Pharmacy Times, p. 25 (April 1982). Y. Okamoto, CHEMTECH. p. 176 (March, 1987). D. R. Snyder, Chromatographia, 19, 352 (1984). J . Bitterová, L. R. 6 (1990). E. Gil-Av, this symposium volume. V. Schurig, M. Jung, D. Schmalzing, M. Schliemer, J. C. A. Peene, and P. C. 13, 470 (1990). R. Dappen, H. R. Mayer, J . Chromatogr. 373, 1 (1986). B. Silber and S. Riegelman, J. Pharmacol. Exp. Ther.

Mayer, J . Chromatogr. 373, 1 (1986). B. Silber and S. Riegelman, J. Pharmacol. Exp. Ther. 215, 643 (1980). S. K r u l l , Advances i n Chromatography, Vol. C. Giddings, E. Grushka, J. R. , Lippincott, Philadelphia, p. 146, 1977. H. Lindner and C. W. , Aster, Springfield, p. 63, 1985. 26 21. 22. 23. 24. 25. 26. ch001 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. CHIRAL SEPARATIONS BY LIQUID CHROMATOGRAPHY C. Pettersson and G. S c h i l l , J . L i q . Chromatogr.

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