Download Distribution and Biological Role. The Chemistry and Biology by Endre A. Balazs, Roger W. Jeanloz PDF
By Endre A. Balazs, Roger W. Jeanloz
The Amino Sugars: The Chemistry and Biology of Compounds Containing Amino Sugars, quantity IIA: Distribution and organic function specializes in the chemistry, actual chemistry, and biochemistry of clearly happening and synthetically ready amino sugars and amino sugar-containing molecules, in addition to the organic and scientific significance of those molecules.
The choice first deals info at the distribution of amino sugars in microorganisms, crops, and invertebrates and amino sugars and macromolecules containing amino sugars in liver. Discussions specialise in microorganisms, invertebrates, amino sugar composition, catabolism of amino sugars, and metabolic interrelationships among amino sugars and different sugars. The textual content then takes a glance at amino sugars and macromolecules containing amino sugars in kidney and amino sugar-containing compounds in urine.
The booklet takes a glance at glycoproteins in salivary glands, saliva, and sputum; glycosaminoglycans and glycoproteins in dermis; and amino sugar-containing compounds in tumors. The textual content additionally evaluates glycosaminoglycans in umbilical twine and glycosaminoglycans and glycoproteins in synovial fluid.
The choice is a accountable reference for readers drawn to the learn of amino sugars.
Read or Download Distribution and Biological Role. The Chemistry and Biology of Compounds Containing Amino Sugars PDF
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Extra resources for Distribution and Biological Role. The Chemistry and Biology of Compounds Containing Amino Sugars
Unidentified amino sugars, however, are known to occur in polysaccharides of Boletus edulis (Dous and Ziegenspek, 1926) and of Coccidioides immitis (Hassid, Baker, and McCready, 1943). Of special interest are the recent reports on the presence of amino sugars in glycopeptides of crystalline Taka-amylase A, an enzyme from Aspergillus oryzae (Hanafusa, Ikenaka, and Akabori, 1955; Tsugita and Akabori, 1959). This appears to be the first indication of the presence of glycoproteins containing amino sugars in fungi.
Amino Sugar Composition A. Hexosamines In Table I are given the values for the hexosamine content of the livers of several species. I t has been pointed out by Boas (1953) that in liver in particular the determination of hexosamines by the ElsonMorgan reaction directly on the tissue hydrolyzate is subject to considerable interference from nonhexosamine chromogens. This interference 47 48 Robert G. Spiro could be eliminated by separation of the amino sugars on Dowex 50 columns, and it was shown that hexosamine values determined directly on the hydrolyzates were 215% higher than those observed with the Dowex 50 separation step.
Isolated from the perchloric acid extract of rat liver (Hurlbert and Potter, 1954) and has been shown to be present in human liver (Table III) and in salmon liver (Tsuyuki, Chang, and Idler, 1958). Pontis (1955) isolated a UDP-iV-acetylhexosamine fraction from bovine liver and showed it to be composed of both UDP-iV-acetylglucosamine and UDP-iV-acetylgalactosamine, with the galactosamine nucleotide making up 25 to 33% of the total. Sialic acid-containing nucleotides have not yet been demonstrated to be present in liver.